Sir John Brydges, 2nd Bt. was born in 1623. He was the son of Sir Giles Brydges, 1st Bt. and Mary Scudamore.1 He married Mary Pearle, daughter of James Pearle.2 He died on 21 February 1651/52 at Bridges Street, Covent Gardens, London, EnglandG, from small pox.1 He was buried at Peterstowe, Herefordshire, EnglandG.1 He died intestate and his estate was administered on 10 March 1651/52.

He succeeded as the 2nd Baronet Brydges, of Wilton, co. Hereford [E., 1627] on 12 September 1637.

He matriculated at Brasenose College, Oxford University, Oxford, Oxfordshire, England, on 4 May 1638.1

His castle at Wilton was burnt by the Royalists, and so he took up with the Parliamentarians, and was instrumental in the surprise of Hereford by the Parliamentarians.